Comparative Dissolution Kinetics of Ibuprofen 200-Mg Capsules (Medisorb Co., Russia) and Ibuprofen 200-Mg Coated Tablets (Biosynthesis Co., Russia)

Autor:	N. A. Prozorova, G. P. Vdovina, A. V. Bobrov
Rok vydání:	2018
Předmět:	Pharmacology Kinetics Pharmacology toxicology Buffer solution Ibuprofen Coated tablets chemistry.chemical_compound chemistry Drug Discovery medicine Expert evaluation Russian federation Dissolution Nuclear chemistry medicine.drug
Zdroj:	Pharmaceutical Chemistry Journal. 52:245-247
ISSN:	1573-9031 0091-150X
DOI:	10.1007/s11094-018-1800-y
Popis:	Experimental data on the comparative dissolution kinetics of two ibuprofen preparations from different manufacturers are presented. The study was performed in three buffer solutions at pH 1.2, 4.5, and 6.8 according to requirements of the Scientific Center for Expert Evaluation of Medicinal Products of the Russian Federation. A fourth dissolution medium was buffer solution at pH 7.2, which is included in a draft regulation. The test used a Erweka DT-720 rotating-basket device.
Databáze:	OpenAIRE
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