Synthesis and transformations of 2-(5-amino-(mercapto)-1,3,4-thiadiazolylthio)-7-methyl-5-oxo-5H-1,3,4-thiadiazolo[3,2-a]pyrimidines

Autor: K. S. Zakharov, M. A. Kukaniev, S. Sh. Shukurov, I. M. Nasyrov, R. A. Karakhanov
Rok vydání: 1993
Předmět:
Zdroj: Russian Chemical Bulletin. 42:1871-1874
ISSN: 1573-9171
1066-5285
DOI: 10.1007/bf00699006
Popis: The reactions of 2-amino-5-mercapto-(or 2,5-dimercapto)-1,3,4-thiadiazoles with 2-bromo-7-methyl-5-oxo-5H-1, 3,4-thiadiazolo[3, 2-a]pyrimidine to give the corresponding sulfides have been studied. The possibility of S-alkylation and addition of quinone at the free mercapto group in the 1,3,4-thiadiazole ring has been shown. The reactions at the amino group with benzoyl chloride and chloroformates have been investigated. The conditions of cyciodehydration at the amino group with ethyl acetoacetate and bromination of the pyrimidine fragment of 7-methyl-5-oxo-5H-1,3,4-thiadiazolo[3,2-a]pyrimidine have been found.
Databáze: OpenAIRE
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