Liquid Chromatographic Determination of Cromolyn Sodium and Related Compounds in Raw Materials

Autor:	Lorna K Rollins, Edward G Lovering, Randy M Duhaime, Dennis J K Gorecki
Rok vydání:	1994
Předmět:	Pharmacology Prima materia Chromatography Cromolyn Sodium Raw material High-performance liquid chromatography Analytical Chemistry chemistry.chemical_compound chemistry Impurity Bromide Phase (matter) Environmental Chemistry Agronomy and Crop Science Quantitative analysis (chemistry) Food Science
Zdroj:	Journal of AOAC INTERNATIONAL. 77:1439-1442
ISSN:	1944-7922 1060-3271
DOI:	10.1093/jaoac/77.6.1439
Popis:	Liquid chromatographic methods for the assay of cromolyn sodium and 3 related compounds were developed. The methods, which differ only in the composition of the mobile phase, use an octadecylsilane bonded-phase column and an acetonitrile–water–cetyltrimethylammonium bromide mobile phase. Minimum quantitatable amounts of the related compounds were less than 0.05%; assay method precision was better than 1 %. Impurity levels in raw material samples from 4 manufacturers were less than 0.1 %.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cc253df71487f79c57d24dfaeaab2b80 https://doi.org/10.1093/jaoac/77.6.1439 Zobrazit plný text záznamu