Similarities in Clinical and Psychosocial Characteristics of Functional Diarrhea and Irritable Bowel Syndrome With Diarrhea

Autor: Sarah Ballou, Prashant Singh, Jesse Katon, Anthony Lembo, Ha-Neul Lee, Joseph Lembo, Daniel Friedlander, Judy Nee, Johanna Iturrino, Vikram Rangan, Courtney McMahon
Rok vydání: 2020
Předmět:
Zdroj: Clinical Gastroenterology and Hepatology. 18:399-405.e1
ISSN: 1542-3565
DOI: 10.1016/j.cgh.2019.08.020
Popis: Background & Aims There have been few published studies of clinical and psychological characteristics of patients with functional diarrhea (FDr). We studied the clinical and psychological characteristics of patients with FDr presenting to a tertiary care clinic, and compared symptom profiles of FDr with those of IBS-diarrhea (IBS-D). Methods Consecutive patients with a diagnosis of FDr (n = 48) or IBS-D (n = 49), per Rome IV criteria, completed a detailed symptom survey from October 2017 through July 2018. Abdominal pain and diarrhea severity were assessed using patient-reported outcomes measurement information system (PROMIS) questionnaires. Patients with anxiety, depression, or sleep disturbances were identified based on PROMIS T-score of 60 or more. Mean and proportions were compared using the Student t test and chi-square analyses, respectively. Results A significantly lower proportion of patients with FDr reported abdominal pain (77.1%) than patients with IBS-D (100%, P Conclusions In an analysis of about 100 patients with FDr or IBS-D, we found overlap in gastrointestinal and psychosomatic symptoms. These 2 entities appear to be a continuum.
Databáze: OpenAIRE