The management of chronic idiopathic urticaria

Autor:	C. E. H. Grattan
Rok vydání:	1992
Předmět:	medicine.diagnostic_test medicine.drug_class business.industry medicine.medical_treatment Terbutaline Dermatology Receptor antagonist Pharmacotherapy Epinephrine Nifedipine Antifibrinolytic agent Erythrocyte sedimentation rate Anesthesia medicine Antihistamine business medicine.drug
Zdroj:	Journal of Dermatological Treatment. 3:85-90
ISSN:	1471-1753 0954-6634
DOI:	10.3109/09546639209089065
Popis:	The cause of chronic urticaria is often elusive and may be multifactorial. Routine laboratory investigations, other than a blood count and erythrocyte sedimentation rate (ESR), are usually unhelpful. Non-specific precipitants, such as food colours and additives and non-steroidal anti-inflammatory drugs, should be avoided if possible. Heat, exercise, stress and alcohol consumption should be minimized. H, receptor blocking antihistamines are the mainstay of drug therapy. A non-sedating antihistamine may usefully be combined with a sedating antihistamine at night if sleep is disturbed. The addition of an H, receptor antagonist may be beneficial. Oral terbutaline and nifedipine can sometimes be effective when taken with antihistamines, probably by inhibiting degranulation. Treatment with antifibrinolytic agents and attenuated androgens should be reserved for severe refractory cases that have not responded to antihistamines. Systemic corticosteroids and adrenaline should only be used for acute disabling attack...
Databáze:	OpenAIRE
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