Pyrrolidine–diaminomethylenemalononitrile organocatalyst for solvent-free asymmetric direct aldol reactions

Autor:	Yuji Koseki, Akichika Itoh, Hiroshi Akutsu, Tsuyoshi Miura, Kosuke Nakashima, Norihiro Tada, Shin-ichi Hirashima
Rok vydání:	2015
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Ketone Solvent free Aldol reaction chemistry Organic Chemistry Drug Discovery Organic chemistry Biochemistry Pyrrolidine
Zdroj:	Tetrahedron Letters. 56:558-561
ISSN:	0040-4039
Popis:	Pyrrolidine–diaminomethylenemalononitrile (pyrrolidine–DMM) organocatalyst has been an efficient reaction medium to promote asymmetric direct aldol reactions to afford the corresponding addition products in high yields with up to 99% ee under solvent-free conditions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cbdb66c4d98a6c1762ab9bc48f2ee7c1 https://doi.org/10.1016/j.tetlet.2014.11.117 Zobrazit plný text záznamu Full Text from ScienceDirect