ВПЛИВ ПРОБІОТИКІВ НА ПОКАЗНИКИ ЕНДОГЕННОЇ ІНТОКСИКАЦІЇ, ІМУНОРЕАКТИВНОСТІ ТА МІКРОБІОЦЕНОЗ КИШЕЧНИКУ ХВОРИХ НА САЛЬМОНЕЛЬОЗ

Autor: L. V. Moroz, O. M. Chemych
Rok vydání: 2017
Předmět:
Zdroj: Інфекційні хвороби.
ISSN: 2414-9969
1681-2727
DOI: 10.11603/1681-2727.2017.1.7768
Popis: The aim of the work – to investigate the effect of probiotics on the course of salmonellosis by studying changes in indicators of endogenous intoxication, immunoreactivity and intestinal microbiota of patients. Patients and Methods. A survey of 189 patients with salmonellosis. The middle age of patients was (43,23±1,22) years. They were taken to hospital at (2,26±0,08) day. Carried out: complete blood count, bacteriological examination of feces, calculated integrative indices of endogenous intoxication and immunoreactivity. Investigated a microbiocenosis of a thick gut prior to treatment and on (5,76±0,16) days from the moment of hospitalization. Results. All patients with salmonellosis in the acute period had a significant increase in integrative indicators of endogenous intoxication. It was followed by violation of immunological reactivity and active adaptive reaction of an organism. All patients have a quantity of bifidobacteria, lactobacilli and escherichia coli were two-three orders less, than in control, at opportunistic pathogen increased by three-six orders of levels of other representatives, hemolyze escherichia coli and fungus class Candida (р
Databáze: OpenAIRE