| Popis: |
Background: Aneurysms have their wall more susceptible to rupture. It is postulated whether the presence of atherosclerotic plaque can influence this, protecting or not. Objective: This review aims to investigate atherosclerosis (AT) as a potential risk factor for rupture of intracranial aneurysms. Design and Setting: this is a literature review, produced in Bahiana School of Medicine and Public Health. Methods: The evaluated studies were obtained in published between 2011 and 2021, using the MeSH terms with following search: ((“atherosclerosis” OR “atherogenesis” OR “atheroscleroses” OR “Vascular Disease”)) AND ((“intracranial aneurysm” OR “brain aneurysm” OR “brain aneurysms” OR “cerebral aneurysm” OR “cerebral aneurysms”)) AND ((“ruptured” OR “rupture” OR “subarachnoid hemorrhage”)). Those that did not correspond the purpose of this review were excluded. Results: 13 of the 103 articles found, were selected. In 03 retrospective cohorts, AT was not a risk factor associated with aneurysm rupture, but a protective factor. In the control case, AT did not obtain statistical significance, but hypercholesterolemia was considered a protective factor. In the postmortem, atheromatous plaque was found only in a one patient who had subarachnoid hemorrhage. The other studies were inconclusive on the subject. Conclusions: Atherosclerosis cannot yet be said as a risk factor for aneurysm rupture due to literary insufficiency. In this way, new research is needed to ensure the evidence. |
