Popis: |
In recent years, the principles and practices of “evidence-based medicine” have received increasing attention and scrutiny in critical care medicine [1, 2, 3]. Evidence-based medicine is defined as the explicit consideration of the best available evidence from scientific research in clinical decision-making. It is acknowledged that scientific knowledge is only one of many determinants to a clinical decision. Said differently, the results of randomized clinical trials (RCTs) (or meta-analyses) do not make clinical decisions, they inform decision makers. Evidence-based medicine provides both a paradigm and a set of principles to help establish the validity of scientific observations. |