Outcome at 1-year adjusted age of 957 infants weighing more than 1250 grams with respiratory distress syndrome randomized to receive synthetic surfactant or air placebo

Autor:	Walker Long, Doug Derleth, Reginald S. Sauve, Charlene M.T. Robertson, David A. Stevenson, Harry Bard, Thomas H. Pauly, Michael Vincer
Rok vydání:	1995
Předmět:	Pediatrics medicine.medical_specialty Respiratory distress business.industry Poison control Adjusted Age Placebo Placebo group law.invention Randomized controlled trial Lung disease law Pediatrics Perinatology and Child Health Medicine Synthetic surfactant business
Zdroj:	The Journal of Pediatrics. 126:S75-S80
ISSN:	0022-3476
Popis:	This study determined outcomes at 12-months adjusted age of 957 infants weighing more than 1250 gm at birth who were subjects in a randomized, double-blind, controlled trial of synthetic surfactant or air placebo administered in a rescue trial at 23 hospitals in the United States and 13 hospitals in Canada. Follow-up results were available for 475 of 563 surviving infants who received air placebo (84%) and 482 of 571 infants who received synthetic surfactant (84%). Developmental outcome was equivalent in the two groups. Morbidity was less in the synthetic surfactant group as assessed by the need for medication for chronic lung disease (52 of 475 [11%] for the air placebo group vs 32 of 482 [7%] for the synthetic surfactant group) or respiratory support (10 of 475 [2%] for the air placebo group vs 1 of 482 [ EDIATR 1995;126:S75-80)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cbb3dd182a905944433d6505342eb99a https://doi.org/10.1016/s0022-3476(95)70011-0 Zobrazit plný text záznamu Full Text from ScienceDirect