Detection of tumor mutant DNA in plasma of patient with colorectal cancer

Autor:	Wen-hui Wan, Jin Gu, Ming Li
Rok vydání:	2002
Předmět:	Oncology CA15-3 Cancer Research medicine.medical_specialty business.industry Colorectal cancer Microsatellite instability Cancer Tumor M2-PK Mouse model of colorectal and intestinal cancer medicine.disease Internal medicine medicine CA19-9 business Tumor marker
Zdroj:	Chinese Journal of Cancer Research. 14:154-156
ISSN:	1993-0631 1000-9604
DOI:	10.1007/s11670-002-0034-3
Popis:	Early diagnosis and prompt treatment are mandatory to prevent colorectal cancer. Detection of free circulating tumor DNA in the serum of the cancer patients provides new possibilities for cancer diagnosis. Several circulating colorectal cancer DNAs have been identified by PCR detection such as the activated K-ras oncogene, inactivated APC, p53 genes, and microsatellite instability (MSI). Circulating tumor DNA was predominantly found in patients with advanced disease and poor prognosis. It was suggested that analysis for circulating tumor DNA might be useful in early diagnosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cbaeeb6de8c36ca074f7120a554882f2 https://doi.org/10.1007/s11670-002-0034-3 Zobrazit plný text záznamu Full text from SpringerLink