Synthesis of spiroindolone scaffolds by Pictet-Spengler spirocyclisation using β-cyclodextrin-SO3H as a recyclable catalyst
| Autor: | Radhika S. Kusurkar, Vaishali S. Shinde, Tukaram D. Urmode, Monali Dawange |
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| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_classification
Aqueous medium Cyclodextrin 010405 organic chemistry Organic Chemistry 010402 general chemistry 01 natural sciences Biochemistry Environmentally friendly Recyclable catalyst 0104 chemical sciences chemistry Yield (chemistry) Drug Discovery Spiroindolone Organic chemistry |
| Zdroj: | Tetrahedron. 73:4348-4354 |
| ISSN: | 0040-4020 |
| DOI: | 10.1016/j.tet.2017.05.089 |
| Popis: | A recyclable catalyst, β-cyclodextrin-SO3H in aqueous medium was used effectively for the synthesis of spiroindolones (tetrahydrospiro-β-carbolines as well as tetrahydrospiro-γ-carbolines) in a Pictet-Spengler spirocyclisation. The products were obtained in good yield in an environmental friendly procedure. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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