Breaking the Silos of Protein Synthesis

Autor: Terri Goss Kinzy, Maria K. Mateyak
Rok vydání: 2017
Předmět:
Zdroj: Trends in Biochemical Sciences. 42:587-588
ISSN: 0968-0004
DOI: 10.1016/j.tibs.2017.06.006
Popis: Protein synthesis requires factors that are proposed to enhance discrete steps. Eukaryotic initiation factor eIF5A was initially thought to affect initiation; however, it was later shown to facilitate translation elongation at polyproline. Recent work by Schuller et al. demonstrates that eIF5A facilitates both general elongation and termination in yeast, challenging these steps as silos.
Databáze: OpenAIRE
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