The association of herpes simplex type 1 encephalitis and anti –N methyl D aspartate receptor antibody encephalitis in a case

Autor: Gülşah Gelişigüzel, Ayşe Büyükdemirci, Sami Kinikli, Cigdem Ataman Hatipoglu, Selin Şenol, Metin Özsoy, Hüseyin Esmer, Salih Cesur, Ulku Oztoprak Siyah
Rok vydání: 2020
Předmět:
Zdroj: Anadolu Güncel Tıp Dergisi. 2:152-155
ISSN: 2667-565X
DOI: 10.38053/acmj.727660
Popis: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a type of autoimmune encephalitis characterized by seizures, psychiatric symptoms, and movement disorder, which may present with an acute or subacute course. It has been reported that the production of anti-NDMA receptor antibodies can be triggered in the course of herpes simplex encephalitis and anti-NMDA receptor encephalitis may occur clinically. It has been reported that 25% of patients with HSV encephalitis have anti-NDMA receptor antibodies and are associated with impaired improvement in cognitive performance. In this article, we present a case of anti-NMDA receptor encephalitis associated with HSV-type 1 encephalitis in a 30-year-old woman and review the literature. After the patient's treatment for HSV encephalitis ended, her psychiatric symptoms such as anxiety, agitation, hallucinations and euphoria persisted and he was diagnosed with anti NMDA receptor antibodies detected in CSF. The patient was transferred to the neurology clinic and intravenous immunoglobulin treatment was started.
Databáze: OpenAIRE