Multiple organ support therapy for the critically ill patient in intensive care
| Autor: | Rihaloo Bellomo, Federico Nalasso, Monica Bonello, Gabriella Salvatori, Ranistha Ratanarat, Alessandra Brendolan, Claudio Ronco, Dimitri Petras, Massimo de Cal |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_specialty
Kidney Physiology Critically ill business.industry medicine.medical_treatment Critical Care and Intensive Care Medicine Critical Care Nursing medicine.disease Intensive care unit Extracorporeal law.invention medicine.anatomical_structure law Intensive care Health care medicine Renal replacement therapy Intensive care medicine business Multiple organ dysfunction syndrome Molecular Biology |
| Zdroj: | Journal of Organ Dysfunction. 1:57-68 |
| ISSN: | 1747-1079 1747-1060 |
| DOI: | 10.1080/17471060500233109 |
| Popis: | Multiple organ dysfunction syndrome is the leading cause of mortality in critically ill patients and is responsible for a large amount of healthcare expenditure. Since the probability of death is directly correlated to the number of failing organs beyond the kidney and the degree of physiological derangement, a clinically sensible approach is to broaden the spectrum of physiological endpoints targeted by extracorporeal therapy. Blood is the vital element that regulates all body systems from cellular to organ level. Continuous renal replacement therapy (CRRT) has direct access to blood and thus to all organ systems. The evolution of CRRT from simple renal replacement to a multiorgan support therapy (MOST) is logical and should be the goal of extracorporeal blood purification in the intensive care unit. This review explains why MOST represents the most logical future conceptual and practical evolution of CRRT and illustrates the biological rationale, supplying animal and clinical evidence that confirms the ... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
| Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |