Synthesis and Conformational Studies of Tertiary Alcohols Derived from Tetrahydro-4H-pyran-4-one and Tetrahydrothiopyran-4-one

Autor:	V. K. Yu, Elizabeth M. Holt, K. D. Praliev, Randal Hallford, K. Darrell Berlin, Kevin Tran, Margaret A. Eastman
Rok vydání:	2005
Předmět:	Chemistry Stereochemistry Aryl Organic Chemistry Infrared spectroscopy chemistry.chemical_element Carbon-13 NMR Ring (chemistry) Biochemistry Sulfur Inorganic Chemistry chemistry.chemical_compound Pyran Reagent Molecule
Zdroj:	Phosphorus, Sulfur, and Silicon and the Related Elements. 180:53-66
ISSN:	1563-5325 1042-6507
Popis:	A series of derivatives of tetrahydro-4 H-pyran-4-one and tetrahydrothiopyran-4-one have been prepared by condensation with aryl Grignard reagents. IR spectra, 1 H and 13 C NMR spectral analyses, and elemental analyses support the structures. A single-crystal X-ray diffraction analysis of 4-(3,5-dimethylphenyl)tetrahydrothiopyran-4-ol [a = 9.729(10), b = 12.846(2), c = 9.970(10) Ai; space group Pna2(1)] confirmed the aryl group is located in a pseudo equatorial position, and the heterocyclic ring is slightly flattened near the sulfur end of the molecule.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cb528a2312db98590e21c1897e0a145b https://doi.org/10.1080/104265090507641 Zobrazit plný text záznamu