Analysis of the survival rate with cervical cancer using137Cs and192Ir afterloading brachytherapy

Autor: Guoxiong Chen, Guixia Zhou, Jianping Sun, Lin Ma, Demei Ma
Rok vydání: 2004
Předmět:
Zdroj: Chinese Journal of Clinical Oncology. 1:106-110
ISSN: 1993-5145
1672-7118
DOI: 10.1007/bf02759457
Popis: OBJECTIVE TO analyze and compare the surwval rate for stages II and III cervical cancer treated by external irradiation plus ~TCs or l~lr. METHODS The patients with cervical cancer were treated by external ~rradiat~on plus ~3:Cs (group A, 427 patients) or plus ~921r (group B, 156 patients). There were 170 stage II cases and 413 stage III cases. The number of cancer types were as follows: squamous cell carcinoma, 524; adenocarc~noma, 34; and adenosquamous cell carcinoma, 25. The two groups received the same external irradiation using 8 or 10 MV of X-ray. After the whole pelvis received 25-35 Gy, the focus was given a total of 45-55 Gy by four divided fields. Intracavitary irradiation was performed with one fraction of 6-7 Gy in reference dose at A point every week and a total dose of 40-60 Gy with 6-8 fractions for group A; every fraction of 5-6 Gy in reference dose of A point and total dose of 30-42 Gy with 5-7 fractions for group B. RESULTS The 5-year survwal rate of stage II and III, and total were 82.9%, 62.2%, and 67.2% for group A respectively and 85.1%, 61.5% and 69.2% for group B respectively. There were significant differences between stage II and Ill in each group (P 0.05). The late complications of the therapy were rectitis and urocystitis and with an incidence rate of 7.3% and 6.3% for group A and 9.6% and 9.0% for group B ( P > 0.05). CONCLUSION The long-term survival rate and complications of stages II andIll cerwcal cancer are similar when treated with external irradiation plus '3:Cs or plus le2ir.
Databáze: OpenAIRE
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