Bi(OTf)3-catalyzed Regioselective Ring Opening of Epoxides with Phenols: Facile Synthesis of 1,3-Diaryloxy-2-propanols

Autor: Mohammed Naseer Ahmed Khan, Syed Ahmed, Mohammed Arifuddin, Ahmed Kamal, Mahendra Sandbhor
Rok vydání: 2005
Předmět:
Zdroj: Chemistry Letters. 34:1142-1143
ISSN: 1348-0715
0366-7022
DOI: 10.1246/cl.2005.1142
Popis: Substituted aryl oxiranes undergo the facile ring opening with phenols in the presence of catalytic amount of bismuth(III) triflate to afford 1,3-diaryloxy-2-propanols in excellent yields under mild conditions. Bismuth(lll) triflate is relatively nontoxic, easy to handle and inexpensive, which makes this procedure particularly attractive for large scale synthesis.
Databáze: OpenAIRE