A presurgical psychosocial intervention for breast cancer patients

Autor: Jan A. Moynihan, Mark R. Larson, Nancy L. Talbot, Paul R. Duberstein, Christopher Caldwell
Rok vydání: 2000
Předmět:
Zdroj: Journal of Psychosomatic Research. 48:187-194
ISSN: 0022-3999
DOI: 10.1016/s0022-3999(99)00110-5
Popis: Objective: The present study evaluated the feasibility and potential immunological benefit of a presurgical intervention for breast cancer patients. Methods: Forty-one newly diagnosed breast cancer patients were randomized into control (standard care) and intervention groups. In addition to standard care, intervention group members received a two-session psychosocial intervention. Blood was drawn at three timepoints: (1) at preintervention; (2) at postintervention/presurgery; and (3) at postsurgery. Results: Examination of the immunological data revealed evidence of suppression of interferon-γ (IFN-γ) in the control group over time, but not in the intervention group. Secondary findings related to psychological assessment generally paralleled the IFN-γ results. Conclusion: The relevance and applicability of these findings to future breast cancer intervention research is detailed.
Databáze: OpenAIRE