Antineovascular effect of α-interferon on corneal neovascularization in rats
| Autor: | Faruk Öztürk, Cevat Can, S. Sami Ilker, Gungor Sobaci |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
genetic structures business.industry medicine.drug_class medicine.medical_treatment Alpha interferon medicine.disease eye diseases Neovascularization Ophthalmology Endocrinology Cytokine Internal medicine Corneal neovascularization medicine Cauterization Corticosteroid sense organs medicine.symptom business Interferon alfa Dexamethasone medicine.drug |
| Zdroj: | Annals of Ophthalmology. 33:35-39 |
| ISSN: | 1558-9951 1530-4086 |
| DOI: | 10.1007/s12009-001-0070-5 |
| Popis: | Clinical and histologic effects of topical recombinant α-interferon (IFN), systemic IFN, topical dexamethasone, and dexamethasone plus topical IFN on corneal neovascularization in response to silver nitrate cauterization were investigated in 110 eyes of 60 Wistar rats. The eyes were evaluated according to the burn stimulus, neovascularization, and histologic inflammation grades 5 days after cauterization. Antineovascular effects of topical and systemic IFN were significantly greater than a placebo but less than dexamethasone alone or in combination with IFN. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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