Abstract 4016: PIK3IP1 regulates prostate cancer cell migration and proliferation and is a noninvasive biomarker of the disease
| Autor: | Andrej Jedinak, Katherine Kaplan, Kevin Loughlin, Marsha Moses |
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| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Cancer Research. 79:4016-4016 |
| ISSN: | 1538-7445 0008-5472 |
| DOI: | 10.1158/1538-7445.am2019-4016 |
| Popis: | Prostate cancer (PCa) is the second most common epithelial cancer in men after lung cancer. PCa shares similar clinical symptoms with benign prostate hyperplasia (BPH) making it very challenging for physicians to make an accurate diagnosis. Prostate specific antigen (PSA) has been used for several decades to facilitate clinical decision making but unfortunately lacks sensitivity and specificity and cannot effectively distinguish between these two prostate diseases. Therefore, there is a need for new biomarkers that can discriminate between these two diseases with high accuracy. Using a global proteomics approach supported by extensive validation, we have found significantly (P Note: This abstract was not presented at the meeting. Citation Format: Andrej Jedinak, Katherine Kaplan, Kevin Loughlin, Marsha Moses. PIK3IP1 regulates prostate cancer cell migration and proliferation and is a noninvasive biomarker of the disease [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 4016. |
| Databáze: | OpenAIRE |
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