A novel Fischer pseudo-benzylic decarboxylation approach to the 1,2,3,4-tetrahydro-cyclopenta[b]indol-3-yl system

Autor:	You-An Ma, Sagun K. Tandel, Antonio Garrido Montalban, Michael J. Martinelli, Steve Johannsen
Rok vydání:	2015
Předmět:	chemistry.chemical_compound Hydrolysis chemistry Decarboxylation Organic Chemistry Drug Discovery Surface modification Organic chemistry Cyclopentanone Biochemistry Tautomer
Zdroj:	Tetrahedron Letters. 56:378-381
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2014.11.101
Popis:	A novel Fischer pseudo-benzylic decarboxylation approach to the 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl system was developed starting from geminally substituted cyclopentanone derivatives and appropriately substituted phenyl hydrazines. In addition, we demonstrate that substituents at the 3- and 7-positions can, for example, be useful synthetic handles for further functionalization.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cadb89a89a3ccc9665c48bf5fc23cd50 https://doi.org/10.1016/j.tetlet.2014.11.101 Zobrazit plný text záznamu Full Text from ScienceDirect