Effect of glycerol on the vestibular labyrinth
| Autor: | Toshiharu Sasano, Shigeto Nakajima, Tetsuya Egami, Ryutaro Murashima, Kohichiro Shigeno |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
medicine.medical_specialty
genetic structures business.industry Endolymph Positional Nystagmus Nystagmus Anatomy eye diseases chemistry.chemical_compound Endolymphatic space medicine.anatomical_structure Otorhinolaryngology chemistry Ophthalmology Vestibular labyrinth medicine Glycerol Glycerol test In patient sense organs Neurology (clinical) medicine.symptom business |
| Zdroj: | Equilibrium Research. 47:155-162 |
| ISSN: | 1882-577X 0385-5716 |
| Popis: | Direction-changing positional nystagmus towards the uppermost ear was noted in 8 of 14 normal subjects and in 7 of 16 patients with Meniere's disease given glycerol (1.5 g/kg). The slow phase velocities of the nystagmus reached a muximum about 3 hours after the oral administration of glycerol.Positional nystagmus was suspected of originating from changes in the specific gravity of the endolymph caused by the infiltration of glycerol into the endolymphatic space, which may indicate that glycerol can pass through the bloodlabyrinth barrier.It may be useful in the investigation of this barrier in patients with Meniere's disease to observe positional nystagmus in response to the glycerol test. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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