Synthesis and antiplatelet activity of DMP 757 analogs

Autor:	Shaker A. Mousa, Alexander L. Johnson, Anju Parthasarathy, Gregory James Wells, John M. Fevig, Ruth R. Wexler, William F. DeGrado, John Wityak, Sharon A. Jackson
Rok vydání:	1995
Předmět:	chemistry.chemical_classification Quantitative structure–activity relationship Chemistry Stereochemistry Organic Chemistry Clinical Biochemistry Drug Discovery Pharmaceutical Science Molecular Medicine Molecular Biology Biochemistry Combinatorial chemistry Cyclic peptide
Zdroj:	Bioorganic & Medicinal Chemistry Letters. 5:2097-2100
ISSN:	0960-894X
DOI:	10.1016/0960-894x(95)00351-s
Popis:	A series of novel cyclic peptides related to DMP 757 bearing heterocyclic and otherwise modified linking moieties were prepared by solution-phase methods. Synthetic methods for the preparation of linking groups and cyclic peptides are presented. In vitro data for the purpose of QSAR is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cad6b8048d2fed6f8d757479f42a4ba1 https://doi.org/10.1016/0960-894x(95)00351-s Zobrazit plný text záznamu Full Text from ScienceDirect