Interaction of humic acid salts with drug preparations
| Autor: | S. L. Khil’ko, R. G. Semenova |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
Drug General Chemical Engineering media_common.quotation_subject Potentiometric titration Natural polymers 02 engineering and technology General Chemistry Polymer 021001 nanoscience & nanotechnology Fuel Technology chemistry Humic acid Organic chemistry Molecule Benzohexonium 0210 nano-technology Macromolecule media_common |
| Zdroj: | Solid Fuel Chemistry. 50:390-394 |
| ISSN: | 1934-8029 0361-5219 |
| DOI: | 10.3103/s0361521916060057 |
| Popis: | The use of natural polymers that form complexes with drug preparations is promising in the development of drugs of new generation. The possibility of complex formation on the interaction of humic acid salts with papaverine, benzohexonium, and B-group vitamins was demonstrated by calorimetric and potentiometric titration. These interactions can occur between the charged groups of a humic acid macroanion and the positively charged centers of drug molecules. The degree of binding of drug preparations by a natural polymer macromolecule can be determined by the charge and the structure of their molecules. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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