Magnetic resonance safety and compatibility of tantalum markers used in proton beam therapy for intraocular tumors: A 7.0 Tesla study
Autor: | Katharina Paul, Lukas Winter, Oliver Stachs, Celal Oezerdem, Jens Heufelder, Laura Boehmert, Andreas Pohlmann, Ira Seibel, Matus Rehak, Till Huelnhagen, Eva Oberacker, Thoralf Niendorf, Andreas Weber |
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Rok vydání: | 2016 |
Předmět: |
Materials science
medicine.diagnostic_test Tantalum Specific absorption rate chemistry.chemical_element Magnetic resonance imaging Proton radiation therapy 030218 nuclear medicine & medical imaging Deflection angle 03 medical and health sciences 0302 clinical medicine Nuclear magnetic resonance chemistry 030220 oncology & carcinogenesis medicine Radiofrequency heating Radiology Nuclear Medicine and imaging Radiation treatment planning Proton therapy |
Zdroj: | Magnetic Resonance in Medicine. 78:1533-1546 |
ISSN: | 0740-3194 |
Popis: | Purpose Proton radiation therapy (PRT) is a standard treatment of uveal melanoma. PRT patients undergo implantation of ocular tantalum markers (OTMs) for treatment planning. Ultra-high-field MRI is a promising technique for 3D tumor visualization and PRT planning. This work examines MR safety and compatibility of OTMs at 7.0 Tesla. Methods MR safety assessment included deflection angle measurements (DAMs), electromagnetic field (EMF) simulations for specific absorption rate (SAR) estimation, and temperature simulations for examining radiofrequency heating using a bow-tie dipole antenna for transmission. MR compatibility was assessed by susceptibility artifacts in agarose, ex vivo pig eyes, and in an ex vivo tumor eye using gradient echo and fast spin-echo imaging. Results DAM (α |
Databáze: | OpenAIRE |
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