Oral candidiasis: Species identification and their antifungal susceptibility pattern in cancer patients receiving radiation therapy
| Autor: | Pratibha Mane, Y. Hyma Pratyusha |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Antifungal
medicine.medical_specialty business.industry medicine.drug_class medicine.medical_treatment Dentistry Cancer medicine.disease Dermatology Oropharyngeal Candidiasis Corpus albicans Radiation therapy Oncology Medicine Species identification Radiology Nuclear Medicine and imaging Colonization business Susceptibility pattern |
| Zdroj: | Journal of Radiotherapy in Practice. 12:100-104 |
| ISSN: | 1467-1131 1460-3969 |
| Popis: | Introduction:Radiotherapy-induced hyposalivation encourages oralCandidacolonization that often leads to oral/pharyngeal candidiasis. The objective of this study was to identify theCandidaspecies in lesions of oropharyngeal candidiasis in patients undergoing radiotherapy for head and neck cancers and to find out antifungal susceptibility pattern.Material and methods:Swabs were collected from 60 patients who developed lesions suggestive of oral candidiasis at the end of 1st week of radiation therapy. Antifungal susceptibility of each of the isolated species was done using disc diffusion method following CLSI guidelines.Results: Candidawas isolated in 13 cases.C.albicans(7) was the most predominant species; a small number of other species have also been identified. Few strains (3) ofCandidashowed variable resistance to the commonly used antifungal drugs.Discussion:The colonization ofCandidamay lead to development of infections with drug-resistant strains, and hence the patients receiving radiation for head and neck cancers should undergo microbiological study for oral candidiasis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|