Comparative evaluation of subarachnoid block with low dose bupivacaine and fentanyl versus low dose bupivacaine and sufentanil in patients undergoing inguinal surgeries
| Autor: | Chelikani Sandeep, D. Malleswara Rao C. H., Teja Kundurthi, A. S. Kameswara Rao |
|---|---|
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | International Journal of Clinical Trials. 6:84 |
| ISSN: | 2349-3259 2349-3240 |
| DOI: | 10.18203/2349-3259.ijct20193214 |
| Popis: | Background: Fentanyl is a phenylpiperidine derivative synthetic opioid agonist. As an analgesic fentanyl is 75-125 times more potent than morphine. Sufentanil is a semisynthetic thienyl analogue fentanyl with analgesic potency 5 to 10 times more than that of fentanyl. Recently there has been an interest in using analgesics and local anaesthetics in an attempt to decrease the local anaesthetic dose enabling faster recovery.Methods: A double blinded randomised study was carried out with 50 patients of ASA grade I and II aged between 20 and 60 years undergoing elective inguinal and below inguinal region surgeries under low dose spinal anaesthesia. Patients received 10 mg of 0.5% hyperbaric bupivacaine with 50 μg of fentanyl added to a total volume of 3 ml (group F), and with sufentanil 5 μg [diluted with 5% dextrose] and volume made to 3 ml (group S). Postoperative VAS score for pain, duration of motor block and complications postoperatively is noted.Results: Prolonged postoperative analgesia was observed in group F (216.7 min) and group S (264.8) which was statistically significant among the groups (pConclusions: When compared to intrathecal bupivacaine-fentanyl combination; intrathecal bupivacaine-sufentanil combination provided prolonged postoperative analgesia with a lesser duration of motor blockade thus allowing early post operative ambulation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|