Mild and Ecofriendly Tandem Synthesis, and Spectral and Antimicrobial Studies of N1-Acetyl-5-aryl-3-(substituted styryl)pyrazolines

Autor:	Neetu Gupta, Vijay Mohan Rao, Vijai N. Pathak, Jaimala Sharma, Rahul Joshi
Rok vydání:	2009
Předmět:	Ethanol Tandem Chemistry Aryl Organic Chemistry Hydrazine Biological activity Antimicrobial Biochemistry Inorganic Chemistry chemistry.chemical_compound Acetic acid Organic chemistry Hydrate
Zdroj:	Phosphorus, Sulfur, and Silicon and the Related Elements. 184:1854-1865
ISSN:	1563-5325 1042-6507
DOI:	10.1080/10426500802388318
Popis:	N1-acetyl-5-aryl-3-(substituted styryl)pyrazolines were synthesized by the cyclocondensation of 1,5-substituted diphenyl-1,4-pentadien-3-ones with hydrazine hydrate and a cyclizing agent such as acetic acid in ethanol. The title compounds were synthesized using conventional and solvent-free approaches, which involves mechano-chemical mixing, microwave-irradiation, and ultrasound-irradiation methods in the presence of a solid support. The synthesized compounds have been characterized by elemental analyses and spectral data (IR, PMR, and FAB-mass). All the synthesized compounds have been evaluated for their antibacterial and antifungal activities. Some compounds have shown promising biological activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ca79bc33ee7cd0aa393f39b2d325e79c https://doi.org/10.1080/10426500802388318 Zobrazit plný text záznamu