The level and daily rhythm of mitotic activity in hypophysectomized rats
| Autor: | L. K. Romanova, G. V. Kharlova, V. F. Sidorova, A. G. Babaeva, Z. A. Ryabinina, L. D. Liozner, N. S. Artem'eva |
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| Rok vydání: | 1963 |
| Předmět: |
Activity level
medicine.medical_specialty Hypophysectomy medicine.medical_treatment General Medicine Biology General Biochemistry Genetics and Molecular Biology Epithelium medicine.anatomical_structure Endocrinology Tongue Cornea Internal medicine medicine sense organs Esophagus Mitosis Rest (music) |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 54:889-892 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf00787646 |
| Popis: | Subject to assessment was the mitotic activity in the epithelium of the cornea, tongue, esophagus, liver, outer orbital gland, renal convoluted tubules of adult hypophysectomized rats (170–210 gm). It was studied at 4, 7, and 10 AM and at 6 and 10 PM; mitoses were calculated as per 4–18 thousand cells. Mitotic activity proved to be the same in the corneal and lingual epithelium of experimental and control animals. Following hypophysectomy the curve of the daily mitotic activity changes exhibited but insignificant changes, i.e., its peak shifted to earlier hours. Mitotic activity level decreased by 45% in the esophageal epithelium; however, its daily rhythm here remained unchanged. Mitotic activity of the epithelium in the rest of the organs decreased 5–12 times, the curve of the daily changes ovtdently remaining unchanged. Thus, hypophysectomy did not eliminate mitosis, even had no decreasing effect on this activity in a number of organs. |
| Databáze: | OpenAIRE |
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