Anti-ulcer and wound healing activity of Ruta graveolens
| Autor: | Shamima A. Rahman, N. Somchit, Abdul Salam Abdullah, Zuraini Ahmad |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
integumentary system biology business.industry Incision wound Ruta graveolens Pharmacology Ulcer index biology.organism_classification digestive system diseases Surgery Complementary and alternative medicine Oral administration medicine business Wound healing Omeprazole medicine.drug |
| Zdroj: | Oriental Pharmacy and Experimental Medicine. 3:147-150 |
| ISSN: | 1598-2386 |
| DOI: | 10.3742/opem.2003.3.3.147 |
| Popis: | The effects of ethanol extract of Ruta graveolens on ulceration induced by ethanol and wound healing properties were investigated in mice. Oral administration of the extract reduced the incidence of ulcer, ulcer index and ulcer length produced by ethanol. The gastroprotective effects of R. graveolens were observed in a dose-dependent manner. However, this activity was statistically less potent than the anti-ulcer drug, omeprazole. When the extract applied on the wound, it promoted wound healing in mice. The wound contraction was faster in these mice when compared to untreated wounds. Based on these present findings, R. graveolens possesses anti-ulcer activity and promotes incision wound healing in mice. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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