Electrochemical oxidative cyclization of N-allylcarboxamides: efficient synthesis of halogenated oxazolines

Autor:	Xiao-Feng Wu, Yanzhao Yin, Yanyang He, Chenwei Liu, Zhiping Yin
Rok vydání:	2022
Předmět:	inorganic chemicals Oxidative cyclization Chemistry Intramolecular force Halogen Materials Chemistry chemistry.chemical_element Lithium General Chemistry Electrochemistry Redox Combinatorial chemistry Catalysis
Zdroj:	New Journal of Chemistry. 46:663-667
ISSN:	1369-9261 1144-0546
DOI:	10.1039/d1nj04819h
Popis:	Herein, we reported an efficient and sustainable intramolecular electrochemical cyclization of N-allylcarboxamides for the synthesis of various halogenated oxazolines. This method was conducted in a simple undivided cell by employing lithium halogen salts as redox mediums and halogen sources. A wide range of oxazolines, including five- and six-membered heterocycles, iodine-, bromo-, and chloro-methyl oxazolines were constructed in moderate to good yields at room temperature. Notably, this electrochemical oxidative cyclization obviates the use of external oxidants.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ca5f367a6b53536d549cdbe5266f3867 https://doi.org/10.1039/d1nj04819h Zobrazit plný text záznamu