Pyrazolones as Building Blocks in Heterocyclic Synthesis: Synthesis of New Pyrazolopyran, Pyrazolopyridazine and Pyrazole Derivatives of Expected Antifungicidal Activity

Autor:	Ibrahim Saad Abdel Hafiz, Mohamed Ahmed Mahmoud Abdel Reheim, Mahmoud M. M. Ramiz, Hatem M. Gaber
Rok vydání:	2012
Předmět:	Pyrazolone General Chemistry Pyrazole Carbon-13 NMR chemistry.chemical_compound chemistry Nucleophile Reagent Electrophile Proton NMR medicine Pyrazolones Organic chemistry medicine.drug
Zdroj:	Journal of the Chinese Chemical Society. 59:72-80
ISSN:	0009-4536
Popis:	A series of new pyrazolone and pyrazole derivatives with expected antifungicidal activity have been prepared through the reactions 3-phenyl-1-H-pyrazol-5(4H)-one (3) and 4-(dimethylaminomethylene)-3-phenyl-1H-pyrazol-5(4H)-one (5) with a variety of electrophilic reagents and nucleophilic reagents. The newly synthesized compounds were characterized by IR, 1H NMR, 13C NMR and mass spectral studies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ca5498cc48cc70ad17c252985a277de3 https://doi.org/10.1002/jccs.201100194 Zobrazit plný text záznamu Plný text