ChemInform Abstract: Catalytic Isonitrile Insertions and Condensations Initiated by RNC-X Complexation

Autor:	Rishabh Mohan, Manasa P. Ravindra, Arpit Doshi, Xun Yang, Fa-Qiang Liu, Suravi Chakrabarty, Dhruv Shah, Fraser F. Fleming, Shruti Choudhary
Rok vydání:	2014
Předmět:	Metal Nucleophile Transition metal Chemistry visual_art Electrophile Large array Rapid access visual_art.visual_art_medium Reactivity (chemistry) General Medicine Combinatorial chemistry Catalysis
Zdroj:	ChemInform. 45
ISSN:	0931-7597
DOI:	10.1002/chin.201437256
Popis:	Isonitriles are delicately poised chemical entities capable of being coaxed to react as nucleophiles or electrophiles. Directing this tunable reactivity with metal and non-metal catalysts provides rapid access to a large array of complex nitrogenous structures ideally functionalized for medicinal applications. Isonitrile insertion into transition metal complexes has featured in numerous synthetic and mechanistic studies, leading to rapid deployment of isonitriles in numerous catalytic processes, including multicomponent reactions (MCR). Covering the literature from 1990–2014, the present review collates reaction types to highlight reactivity trends and allow catalyst comparison.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ca5452e67a258d4e7f306a05f3fc1d1a https://doi.org/10.1002/chin.201437256 Zobrazit plný text záznamu Plný text