In vitro inhibition of human nucleoside transporters and uptake of azacitidine by an isocitrate dehydrogenase-2 inhibitor enasidenib and its metabolite AGI-16903
| Autor: | Zeen Tong, Matthew Hoffmann, James D. Young, Sylvia Y.M. Yao, Usha Yerramilli, Sekhar Surapaneni |
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| Rok vydání: | 2018 |
| Předmět: |
Health
Toxicology and Mutagenesis Metabolite Azacitidine Xenopus Enasidenib Nucleoside transporter Toxicology 030226 pharmacology & pharmacy Biochemistry law.invention 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine law medicine Pharmacology biology Chemistry Transporter General Medicine biology.organism_classification 030220 oncology & carcinogenesis biology.protein Recombinant DNA Nucleoside medicine.drug |
| Zdroj: | Xenobiotica. 49:1229-1236 |
| ISSN: | 1366-5928 0049-8254 |
| DOI: | 10.1080/00498254.2018.1539783 |
| Popis: | 1. The present study investigated inhibitory effects of enasidenib and its metabolite AGI-16903 on (a) recombinant human nucleoside transporters (hNTs) in hNT-producing Xenopus laevis oocytes, and ... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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