Antimicrobial Properties of Corn Stover Lignin Fractions Derived from Catalytic Transfer Hydrogenolysis in Supercritical Ethanol with a Ru/C Catalyst
| Autor: | Jian Shi, Justin K. Mobley, Masoumeh Dorrani, Xiaowen Chen, Bert C. Lynn, Shardrack O. Asare, Wenqi Li, Ryan M. Kalinoski |
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| Rok vydání: | 2020 |
| Předmět: |
Chloroform
Renewable Energy Sustainability and the Environment Depolymerization General Chemical Engineering Ethyl acetate Syringol Ether 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences chemistry.chemical_compound Corn stover chemistry Environmental Chemistry Organic chemistry Lignin Petroleum ether 0210 nano-technology |
| Zdroj: | ACS Sustainable Chemistry & Engineering. 8:18455-18467 |
| ISSN: | 2168-0485 |
| DOI: | 10.1021/acssuschemeng.0c05812 |
| Popis: | Converting lignin to value-added products at high yields provides an avenue for making ethanol biorefineries more profitable while reducing the carbon footprint of products generally derived from petroleum. In this study, corn stover lignin was depolymerized by catalytic transfer hydrogenolysis (CTH) in supercritical ethanol with a Ru/C catalyst. The lignin-derived bio-oil was then sequentially extracted utilizing hexane, petroleum ether, chloroform, and ethyl acetate as solvents in order of less polar to polar, and the subsequent bio-oils were characterized using GPC, GC/MS, and HSQC NMR. Results show that the monomers in the bio-oil fractions contained primarily alkylated phenols, hydrogenated hydroxycinnamic acid derivatives, syringol and guaiacol-type lignins created from reductive cleavages of ether linkages, which were sequentially extracted into groups depending on the solvent polarity. The antimicrobial properties of the bio-oils were screened against Gram-positive (Bacillus subtilis, Lactobacillus amylovorus, and Staphylococcus epidermidis) and Gram-negative (Escherichia coli) bacteria and yeast (Saccharomyces cerevisiae) by examining microbial growth inhibition. Results show that CTH-derived bio-oils inhibited all tested organisms at concentrations less than 3 mg/mL. Total monomer concentration and the presence of specific monomers (i.e., syringyl propane) showed correlations to antimicrobial activity, likely due to cell death or membrane damage. This study provides insights into using sequential extraction to fractionate lignin-derived compounds and correlations between the properties of the extracted compounds and their antimicrobial activity. |
| Databáze: | OpenAIRE |
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