Consequences of electroplated targets on radiopharmaceutical preparations

Autor: A. Knott, Steven M. Larson, Y. Sheh, A.S. Gelbard, J.R. Dahl, S. Tirelli, Ronald D. Finn
Rok vydání: 1991
Předmět:
Zdroj: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. :1284-1286
ISSN: 0168-583X
DOI: 10.1016/0168-583x(91)95152-4
Popis: The staff of the cyclotron facility at Memorial Sloan-Kettering Cancer Center is involved in a comprehensive radionuclide preparation program which culminates with the formulation of numerous requested short-lived, positron-emitting radiopharmaceutical agents for clinical investigation. Both the produced radionuclide as well as the final radiolabeled compound are subjected to stringent quality control standards including assays for radiochemical and chemical purity. The subtle chemical consequences resulting from the irradiation of a nickel-plated target for 13N production serve to emphasize some of these potential technical difficulties.
Databáze: OpenAIRE