Delayed Radiation Injury to the Retrobulbar Optic Nerves and Chiasm
| Autor: | Dermot Roden, Robert C. Sergott, Peter J. Savino, Norman J. Schatz, James Clark, Barbara Fowble, Thomas M. Bosley |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Chemotherapy
medicine.medical_specialty genetic structures medicine.diagnostic_test business.industry medicine.drug_class Lumbar puncture medicine.medical_treatment Eye disease medicine.disease eye diseases Surgery Radiation therapy Ophthalmology Optic chiasma Optic nerve Medicine Corticosteroid business Complication |
| Zdroj: | Ophthalmology. 97:346-351 |
| ISSN: | 0161-6420 |
| DOI: | 10.1016/s0161-6420(90)32582-4 |
| Popis: | Thirteen patients with delayed radiation injury to the optic nerves and chiasm were treated with hyperbaric oxygen (HBO) and corticosteroids. These patients experienced painless, abrupt loss of vision in one (6 patients) or both (7 patients) eyes between 4 and 35 months after receiving radiation doses of at least 4500 cGy to the region of the chiasm. Diagnostic evaluation including neuro-imaging and lumbar puncture showed no recurrent tumor and no other cause for visual loss. No patient's vision improved during treatment or follow-up lasting between 1 and 4 years. There were no serious complications of treatment. |
| Databáze: | OpenAIRE |
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