Lack of Correlation between the Location of Choroidal Melanoma and Ultraviolet-Radiation Dose Distribution

Autor: Laurent H. Schwartz, Regis Ferrand, Pierre Yves Boelle, C. Maylin, François D'Hermies, Jean Virmont, Francois D'Hermies
Rok vydání: 1997
Předmět:
Zdroj: Radiation Research. 147:451
ISSN: 0033-7587
DOI: 10.2307/3579502
Popis: Ocular melanomas arise from the choroid. The results of our study of a total of 92 ocular melanomas would indicate that there is no preferential location for tumors on the eye. We estimated the ultraviolet (UV) radiation dose distribution using data available in the literature. We then compared tumor location and UV-radiation dose distribution. UVC and UVB do not reach the choroid, and UVA is filtered by the cornea and the lens. Only a small percentage of the incoming rays reach the posterior and inferior part of the retina, but none reach the superior and anterior part of the eye. We concluded that it is therefore very unlikely that UV-radiation exposure is responsible for choroidal melanoma.
Databáze: OpenAIRE