Alkali-labile gangliosides
| Autor: | Laura Mauri, Sandro Sonnino |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Glycoconjugate Journal. 40:269-276 |
| ISSN: | 1573-4986 0282-0080 |
| DOI: | 10.1007/s10719-023-10103-0 |
| Popis: | The structure and properties of a group of gangliosides modified by mild alkaline treatment are discussed. We will present the occurrence and the structure of gangliosides carrying the N-acetyneuraminic acid O-acetylated in position 9, the Neu5,9Ac2, and of gangliosides carrying a sialic acid that forms a lactone ring. Starting from biochemical data we will discuss the possible biochemical role played by these gangliosides in the processes of cell signaling and maintenance of brain functions. |
| Databáze: | OpenAIRE |
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