Premature decline of the testicular endocrine function in rats with hereditary galactosemia
| Autor: | K. V. Svechnikov, A. V. Osadchuk, Solov'eva Na, Svechnikova Ig, Akhmerova Lg |
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| Rok vydání: | 1996 |
| Předmět: |
endocrine system
medicine.medical_specialty medicine.drug_class Galactosemia Stimulation General Medicine Biology medicine.disease General Biochemistry Genetics and Molecular Biology Muscle hypertrophy chemistry.chemical_compound Basal (phylogenetics) Endocrinology chemistry Internal medicine Galactose medicine Endocrine system Gonadotropin Testosterone |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 122:929-931 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf02446585 |
| Popis: | Testicular endocrine function and morphometric characteristics of the genital system are examined in W/SSM (galactose sensitive) and R (galactose resistant) rats aging 3 and 10 months. Testicular hypertrophy (in comparison with R rats) is found in W/SSM rats of both ages. Basal plasma testosterone levels in young and old rats of both strains did not differ. Afterin vivo stimulation of the testes with chorionic gonadotropin, the increment of plasma testosterone in 10-month-old W/SSM rats was 2-fold lower than in young rats and in age-matching R rats. Premature decrease of testicular endocrine function in W/SSM may reflect a more intense aging of these animals. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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