Submandibular (Undescended) Ectopic Parathyroid Glands: Elusive to Surgeons and Localization Studies

Autor: Daniel W. Karakla, Marc L. Silverberg, Suhyla Alam, Peter G. Volsky, J. Trad Wadsworth
Rok vydání: 2013
Předmět:
Zdroj: Otolaryngology–Head and Neck Surgery. 149
ISSN: 1097-6817
0194-5998
DOI: 10.1177/0194599813496044a164
Popis: Objectives:High cervical parathyroid adenomas, known as undescended adenomas, occur with a frequency of less than 0.1%, but account for 7% of failed parathyroidectomies. Such cases are scarce in the otolaryngology-head and neck surgery literature. Preoperative localization of undescended adenomas using Technetium 99-c sestamibi scintigraphy (sestamibi) is difficult due to uptake and retention of sestamibi by salivary gland tissue.Methods:We present a review of the literature and two surgeons’ experience involving undescended parathyroid glands complicating the treatment of patients with primary (cases 2,3) and secondary (case 1) hyperparathyroidism. In case 1, a 52-year-old dialysis-dependent male experienced recurrent secondary hyperparathyroidism, requiring three operations over two years to excise all parathyroid glands. The right inferior gland was localized to the submandibular region prior to the final operation. In case 2, two sestamibi–single-photon emission computed tomography scans were proven i...
Databáze: OpenAIRE