Sudden cardiac death following adriamycin therapy
| Autor: | Kevin K. Loh, Rex D. Couch, Jean Sugino |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Melphalan
Cancer Research medicine.medical_specialty Vincristine Chemotherapy business.industry medicine.medical_treatment Cardiomyopathy medicine.disease Sudden death Surgery Sudden cardiac death Oncology Internal medicine Ventricular fibrillation medicine Cardiology Cardiopulmonary resuscitation business medicine.drug |
| Zdroj: | Cancer. 48:38-39 |
| ISSN: | 1097-0142 0008-543X |
| DOI: | 10.1002/1097-0142(19810701)48:1<38::aid-cncr2820480109>3.0.co;2-h |
| Popis: | An 18-year-old man had had an osteogenic sarcoma of the distal tibia at age 16. Below-knee amputation was carried out and followed by adjuvant chemotherapy with Adriamycin, vincristine, methotrexate, Cytoxan, and melphalan. One month after termination of chemotherapy, he died suddenly while playing tennis. Documented ventricular fibrillation was unresponsive to cardiopulmonary resuscitation. Myocardial fibrosis ("cardiomyopathy") was the only significant anatomic finding at autopsy. The occurrence of sudden death without antecedent cardiac failure may have been related to strenuous physical activity in this patient who had received combined adjuvant chemotherapy. |
| Databáze: | OpenAIRE |
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