Effect of atenolol and propranolol on the systemic and regional hemodynamics
Autor: | F. E. Meertsuk, A. V. Val'dman, Sh. I. Ismailov, S. D. Yuzhakov, Medvedev Os, M. D. Mashkovskii |
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Rok vydání: | 1983 |
Předmět: |
medicine.medical_specialty
Cardiac output business.industry Stomach Hemodynamics General Medicine Propranolol Blood flow Atenolol General Biochemistry Genetics and Molecular Biology medicine.anatomical_structure Blood pressure Internal medicine Renal blood flow Cardiology medicine business medicine.drug |
Zdroj: | Bulletin of Experimental Biology and Medicine. 96:949-951 |
ISSN: | 1573-8221 0007-4888 |
DOI: | 10.1007/bf00833046 |
Popis: | Experiments on anesthetized rats were made to study the effects of atenolol and propranolol on cardiac output and distribution of the drugs in the heart, lungs, brain, kidneys, large and small intestines, stomach, liver and skeletal muscles with the use of radioactive carbonized microspheres techniques. Atenolol and propranolol provoked a decrease in cardiac output and raised the total peripheral resistance without a detectable effect on blood pressure. Administration of atenolol brought about a decrease in the renal blood flow whereas that of propranolol in the myocardial blood flow. |
Databáze: | OpenAIRE |
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