Mannose-mediated nanodelivery of methotrexate to macrophages augments rheumatoid arthritis therapy

Autor:	Liang Yang, Yongjie Sha, Yuansong Wei, Hanghang Fang, Jingjing Jiang, Lichen Yin, Zhiyuan Zhong, Fenghua Meng
Rok vydání:	2023
Předmět:	Biomedical Engineering General Materials Science
Zdroj:	Biomaterials Science. 11:2211-2220
ISSN:	2047-4849 2047-4830
DOI:	10.1039/d2bm02072f
Popis:	Inflammation targeted delivery of methotrexate using mannose-installed polymersomes (Man-PMTX) can repolarize macrophages from M1 type to M2 type and mitigate proinflammatory cytokines, leading to effectively augmented rheumatoid arthritis therapy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ca028c92bb57b4c18194c01bd5f91ee8 https://doi.org/10.1039/d2bm02072f Zobrazit plný text záznamu