High Relaxivity Magnetic Resonance Imaging Contrast Agents Part 1
| Autor: | Joel T. Welch, Vincent Jacques, Heribert Schmitt-Willich, Jeffrey S. Troughton, Jaclyn M. Chasse, Peter Caravan, Stephane Dumas, Wei-Chuan Sun |
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| Rok vydání: | 2010 |
| Předmět: |
biology
medicine.diagnostic_test Extramural Gadolinium Relaxation (NMR) Serum albumin chemistry.chemical_element Magnetic resonance imaging General Medicine Plasma protein binding Water exchange Nuclear magnetic resonance chemistry Atom biology.protein medicine Radiology Nuclear Medicine and imaging |
| Zdroj: | Investigative Radiology. 45:600-612 |
| ISSN: | 0020-9996 |
| Popis: | Rationale and Objectives:The donor atoms that bind to gadolinium in contrast agents influence inner-sphere water exchange and electronic relaxation, both of which determine observed relaxivity. The effect of these molecular parameters on relaxivity is greatest when the contrast agent is protein boun |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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