Pathogenic Studies and Antigenic and Sequence Comparisons of A/Equine/Alaska/1/91 (H3NS) Influenza Virus

Autor: Sudhir P. Sahu, Douglas D. Pedersen, Arnold D. Alstad, Robert G. Webster, Yoshihiro Kawaoka, Dennis A. Saari
Rok vydání: 1993
Předmět:
Zdroj: Journal of Veterinary Diagnostic Investigation. 5:8-11
ISSN: 1943-4936
1040-6387
DOI: 10.1177/104063879300500103
Popis: An influenza virus, A/equine/Alaska/1/91 (H3N8), was isolated from horses from Alaska with an acute respiratory infection. Pathogenic and serologic studies revealed that this virus is similar to previously isolated equine H3N8 influenza viruses. Antigenic analyses utilizing hemagglutination inhibition and neuraminidase inhibition assays indicated an antigenic drift from the prototype equine H3N8 influenza virus, A/equine/Miami/1/63. Partial sequence analysis of the A/equine/Alaska influenza virus indicated that each of 8 gene sequences are of equine origin.
Databáze: OpenAIRE