Radical cyclisation reactions involving phosphonyl radicals: the use of phosphites and phosphine oxides as alternatives to tributyltin hydride

Autor:	Bala Upeandran, Jenny M. Barks, Andrew F. Parsons, Bruce C. Gilbert
Rok vydání:	2001
Předmět:	chemistry.chemical_classification Diene Radical Organic Chemistry Tributyltin hydride Hydrogen atom Diphenylphosphine oxide Biochemistry Medicinal chemistry Solvent chemistry.chemical_compound chemistry Drug Discovery Organophosphorus compound Phosphine
Zdroj:	Tetrahedron Letters. 42:3137-3140
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(01)00370-7
Popis:	Free radical cyclisation of a variety of 1,6-dienes using CCl 4 in the presence of diethyl phosphite or diphenylphosphine oxide has been investigated. These reactions involve addition of the trichloromethyl radical to the diene followed by a 5- exo - trig cyclisation reaction. The resultant cyclic primary radical can abstract a chlorine atom from CCl 4 or alternatively, abstract a hydrogen atom from the solvent or the organophosphorus compound.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c9a29c0a8432abb058127214f7197558 https://doi.org/10.1016/s0040-4039(01)00370-7 Zobrazit plný text záznamu Full Text from ScienceDirect