Amorphous silicon based photodetectors for biosensing
| Autor: | J. Thielmann, C. Harendt, Dominik Furin, Marc Sämann, Markus B. Schubert, G. Gauglitz |
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| Rok vydání: | 2011 |
| Předmět: |
Amorphous silicon
Materials science genetic structures Silicon business.industry Microfluidics Photodetector chemistry.chemical_element eye diseases Photodiode law.invention chemistry.chemical_compound Reflectometric interference spectroscopy chemistry law Miniaturization Optoelectronics sense organs business Biosensor |
| Zdroj: | 2011 Conference on Lasers and Electro-Optics Europe and 12th European Quantum Electronics Conference (CLEO EUROPE/EQEC). |
| Popis: | Thin film photodiodes open interesting possibilities for enhancing well known optical detection methods in biosensing [1,2]. This contribution focuses on the development of a portable point-of-care (POCT) sensor system based on the direct optical and label-free detection of proteins by Reflectometric Interference Spectroscopy (RIfS) [3]. But more generally, the integration of amophous silicon (a-Si) based photodiodes into microfluidic sample handling environments enables miniaturization and parallelization of several optical techniques for biosensing, e.g. fluorescence labelling for DNA detection [4], chemiluminescence [5], or optical absorption [6] of appropriately labelled proteins. |
| Databáze: | OpenAIRE |
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