| Autor: |
Diego Basile Colugnati, Cleber Alexandre de Oliveira, M. M. de Albuquerque, Fulvio A. Scorza, J. B. da Ponte, M. S. R. de Oliveira, Ricardo Mario Arida |
| Rok vydání: |
2007 |
| Předmět: |
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| Zdroj: |
IV Latin American Congress on Biomedical Engineering 2007, Bioengineering Solutions for Latin America Health ISBN: 9783540744702 |
| DOI: |
10.1007/978-3-540-74471-9_244 |
| Popis: |
Studies has showed beneficial effects of physical exercise in epilepsy. Thus, sudden death in epileptic patients is higher than in no epileptic. It is well known the positive effects of exercise to the prevention and rehabilitation of cardiac diseases. Based on this, we analyzed the heart rate in vivo and in vitro and the ventricular pressure in vitro of rats with epilepsy submitted to an aerobic physical exercise program. Adult male Wistar rats were divided into 4 groups of 6 animals: epilepsy group, trained epilepsy group, control group, trained control group. The pilocarpine model was used to obtain epilepsy groups. Trained groups were submitted to aerobic exercise program consisting of 30 days during 50 min at 60% of VO2 max. Our results showed difference in heart rate in vivo only in animals with epilepsy when compared with control animals. A significant difference in heart rate in vitro was observed in trained animals with epilepsy when compared with animals with epilepsy. No significant difference in the ventricular pressure in vitro was observed among all groups. These results suggest an altered intrinsic autorhythmicity of trained animals with epilepsy, however, without altered heart contractility function. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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